Techniques For Rapid Detection And Quantitation Of Volatile Organic Compounds (vocs) Using Breath Samples
An exemplary breath analysis system may include a sampling chamber having a molecule collector disposed therein. The molecule detector may be configured such that volatile organic compounds (VOCs) present in a breath sample introduced to the sampling chamber adhere to the molecule collector. A heating element may introduce heat within the sampling chamber, causing release of at least a portion of the VOCs adhered to the molecule collector. An analysis device (e.g., a mass spectrometer or tetrahertz (THz) spectrometer) may identify one or more target VOCs from among at least the portion of the VOCs released from the molecule collector and generate an output representative of the identified one or more target VOCs. The output may include information that quantitates a concentration of the one or more target VOCs with respect to a source of the breath sample.
Claim CLM-00001. 1. A system for analyzing a breath sample, the system comprising:
a sampling chamber; an inlet coupled to the sampling chamber and configured to receive a breath sample and to provide the breath sample to the sampling chamber; a molecule collector disposed within the sampling chamber, wherein the molecule collector is configured to adhere to volatile organic compounds (VOCs) present in the breath sample; a heating element configured to introduce heat within the sampling chamber; an analysis device configured to:
identify one or more target VOCs from among the VOCs present in the sampling chamber subsequent to release of at least a portion of the VOCs from the molecule collector, wherein at least the portion of the VOCs are released from the molecule collector by the heat introduced within the sampling chamber by the heating element; andgenerate an output representative of the one or more target VOCs.
Claim CLM-00014. 14. A method for analyzing a breath sample, the method comprising:
receiving, at a sampling chamber, a breath sample via an inlet coupled to the sampling chamber, wherein the sampling chamber comprises a molecule collector disposed within the sampling chamber, and wherein the molecule collector is configured to adhere to volatile organic compounds (VOCs) present in the breath sample; introducing, via a heating element, heat within the sampling chamber; identifying, by an analysis device, one or more target VOCs from among the VOCs present in the sampling chamber subsequent to release of at least a portion of the VOCs from the molecule collector, wherein at least the portion of the VOCs are released from the molecule collector by the heat introduced within the sampling chamber by the heating element; and generating, by the analysis device, an output representative of the one or more target VOCs, wherein the output representative of the one or more target VOCs comprises information that quantitates a concentration of the one or more target VOCs with respect to a source of the breath sample.
Claim CLM-00020. 20. A non-transitory computer-readable storage medium storing instructions that, when executed by one or more processors, cause the one or more processors to perform operations for analyzing a breath sample, the operations comprising:
activating a heating element configured to introduce heat within a sampling chamber subsequent to a breath sample being provided to the sampling chamber, wherein the sampling chamber comprises a molecule collector disposed within the sampling chamber, and wherein the molecule collector is configured to adhere to volatile organic compounds (VOCs) present in the breath sample; identifying one or more target VOCs from among the VOCs present in the sampling chamber subsequent to release of at least a portion of the VOCs from the molecule collector, wherein at least the portion of the VOCs are released from the molecule collector by the heat introduced within the sampling chamber by the heating element, and wherein the one or more target VOCs include Δ-9-THC, 11-hydroxy-tetrahydrocannabinol (11-OH-THC), carboxy-tetrahydrocannabinol (THC-COOH), THC metabolites, opioids, opioid metabolites, or a combination thereof; and generating an output representative of the one or more target VOCs, wherein the output representative of the one or more target VOCs comprises information that quantitates a concentration of the one or more target VOCs with respect to a source of the breath sample.
