Abstract: |
Provided herein are pharmaceutical formulations, methods for their production, and uses thereof. The pharmaceutical formulations comprise a salt of an optionally substituted dimethyltryptamine compound, a buffer, which is separate to the salt, and water. The formulations have pH values of from about 3.5 to about 6.5 and osmolalities of about 250 to about 350 mOsm/Kg. Such formulations are suitable for injection, being both stable and clinically acceptable, and have potential uses in the treatment of psychiatric or neurological disorders. |
Inventor: |
Layzell, Marie Claire (London, GB); Rennie, James Maxwell (London, GB) |
Applicant: |
SMALL PHARMA Ltd (London, GB) |
Face Assignee: |
SMALL PHARMA Ltd (London, GB) |
Filed: |
2021-08-27 |
Issued: |
2022-03-03 |
Claims: |
20 |
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US20220062238
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1. A pharmaceutical formulation suitable for injection, comprising:
(14)
(4)
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