Application US20210100999

DEVICES AND METHODS FOR CONTROLLING TREMOR
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US20210100999

1-19. (canceled) (0)

20. A method for transcutaneously stimulating afferent peripheral nerves of a stroke patient, the method comprising: (11) (7)

measuring one or more characteristics of a tremor of the patient using one or more wearable sensors;

analyzing data from the one or more wearable sensors to calculate a fraction of a period of the tremor;

positioning a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve;

positioning a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve;

delivering a first electrical stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and

delivering a second electrical stimulus to the second afferent peripheral nerve through the second peripheral nerve effector,

wherein the second electrical stimulus is offset in time from the first electrical stimulus by the calculated fraction of the tremor period, wherein the calculated fraction is at least about a quarter of the tremor period.

21. The method of claim 20, wherein the calculated fraction is one half of the tremor period, wherein the first electrical stimulus comprises a frequency of about 150 Hz, wherein analyzing data comprises performing a frequency analysis of the spectral power of motion data on a predetermined length of time of the motion data, wherein the frequency analysis is restricted to between about 4 Hz to about 12 Hz, and wherein the first electrical stimulus and the second electrical stimulus comprise burst stimuli. (0)

22. The method of claim 20, wherein the calculated fraction is one half of the tremor period. (0)

23. The method of claim 20, wherein the calculated fraction is one quarter of the tremor period. (0)

24. The method of claim 20, wherein the first electrical stimulus comprises a frequency of between about 50 Hz to about 300 Hz. (0)

25. The method of claim 20, wherein the first electrical stimulus comprises a frequency of about 150 Hz. (0)

26. The method of claim 20, wherein the first electrical stimulus comprises a burst stimulus. (0)

27. The method of claim 20, wherein analyzing data comprises performing a frequency analysis of the spectral power of motion data on a predetermined length of time of the motion data, wherein the frequency analysis is restricted to between about 4 Hz to about 12 Hz. (0)

30. The method of claim 20, wherein the calculated fraction is one half of the tremor period. (0)

31. The method of claim 20, wherein the calculated fraction is one quarter of the tremor period. (0)

32. The method of claim 20, further comprising varying the frequency of the first electric stimulus over time. (0)

33. The method of claim 20, further comprising repeating the first electrical stimulus and the second electrical stimulus in cycles. (0)

28. A method for transcutaneously stimulating afferent peripheral nerves of a patient, the method comprising: (1) (7)

measuring one or more characteristics of a resonant circuit of the patient using one or more wearable sensors;

analyzing data from the one or more wearable sensors to calculate a fraction of a period of the resonant circuit;

positioning a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve;

positioning a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve;

delivering a first electrical stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and

delivering a second electrical stimulus to the second afferent peripheral nerve through the second peripheral nerve effector,

wherein the second electrical stimulus is offset in time from the first electrical stimulus by the calculated fraction of the period of the resonant circuit, wherein the calculated fraction is selected from the group consisting of one half of the period of the resonant circuit, one quarter of the period of the resonant circuit, and three fourths of the period of the resonant circuit.

29. The method of claim 28 further comprising repeating the first electrical stimulus and the second electrical stimulus in cycles, wherein the calculated fraction is one half of the tremor period, wherein analyzing data comprises performing a frequency analysis of the spectral power of data on a predetermined length of time of the data, wherein the first electrical stimulus and the second electrical stimulus comprise burst stimuli, and wherein the patient is a stroke patient. (2) (0)

36. A system for transcutaneously stimulating afferent peripheral nerves, the system comprising: (3) (8)

one or more wearable sensors measuring one or more characteristics of a resonant circuit of the patient;

a controller configured to analyze data from the one or more wearable sensors to calculate a fraction of a period of the resonant circuit;

a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve;

a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve,

wherein the controller is configured to cause the system to:

deliver a first stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and

deliver a second stimulus to the second afferent peripheral nerve through the second peripheral nerve effector,

wherein the second stimulus is offset in time from the first electrical stimulus by the calculated fraction of the period of the resonant circuit, wherein the calculated fraction is selected from the group consisting of one half of the period of the resonant circuit, one quarter of the period of the resonant circuit, and three fourths of the period of the resonant circuit.

37. The system of claim 36, wherein the controller is further configured to cause the system to: repeat the first stimulus and the second stimulus in cycles, wherein the calculated fraction is one half of the tremor period, wherein analyzing data comprises performing a frequency analysis of the spectral power of data on a predetermined length of time of the data, wherein the first electrical stimulus and the second electrical stimulus comprise electrical burst stimuli, and wherein the patient is a stroke patient. (0)

38. The system of claim 36, wherein the calculated fraction is one half of the tremor period. (0)

39. The system of claim 36, wherein the patient is a stroke patient. (0)

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Application US20210100999

DEVICES AND METHODS FOR CONTROLLING TREMOR

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