Patent US10722490

Water soluble compositions comprising purified cannabinoids
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US10722490

1. A liquid composition, comprising: (8) (4)

one or more purified cannabinoids;

one or more purified terpenes;

Vitamin E TPGS; and

water.

2. The liquid composition of claim 1, comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 85:15 to about 75:25 by percent mass. (0)

3. The liquid composition of claim 1, comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 82:18 to about 78:22 by percent mass. (0)

4. The liquid composition of claim 1, comprising a micelle. (1) (0)

9. The liquid composition of claim 1, wherein the one or more purified cannabinoids is THCA, CBC, THC, CBN, CBD, CBG, CBGA, CBDA, or a combination thereof. (0)

10. The liquid composition of claim 1, wherein the one or more purified cannabinoids is CBD, THC, THCV, or a combination thereof. (1) (0)

12. The liquid composition of claim 1, wherein the one or more purified terpenes is linalool, alpha-pinene, alpha-humulene, terpinolene, eucalyptol, pulegone, terpineol, beta-caryophyllene, cymene, or a combination thereof. (0)

15. The liquid composition of claim 1, comprising a ratio of Vitamin E TPGS to a combined amount of the one or more purified cannabinoids and the one or more purified terpenes of about 85:15 to about 75:25 by percent mass. (0)

16. The liquid composition of claim 1, comprising a ratio of Vitamin E TPGS to a combined amount of the one or more purified cannabinoids and the one or more purified terpenes of about 85:15 to about 75:25 by percent mass. (0)

5. A method of making a liquid composition having one or more purified cannabinoids and one or more purified terpenes, comprising: (1) (5)

separating one or more purified cannabinoids and one or more purified terpenes from a cannabis plant material;

adding the one or more purified cannabinoids and the one or more purified terpenes to Vitamin E TPGS to create a mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more purified terpenes;

heating said mixture to a first temperature;

adding water to the mixture to create an aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes; and

cooling the aqueous formulation to a second temperature.

6. The method of claim 5, comprising: (3) (5)

sonicating the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes to create micelles;

freezing the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes;

lowering pressure of the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes;

removing water from the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes to create a dry powder; and

adding water to the dry powder to create a liquid cannabinoid composition comprising Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes.

7. The method of claim 6, wherein the dry powder comprises reverse micelles. (0)

8. The method of claim 6, wherein the first temperature is between 70-90 degrees Celsius; and wherein the second temperature is between 0-50 degrees Celsius. (0)

17. The method of claim 6, wherein adding water to the dry powder creates a liquid cannabinoid composition comprising Vitamin E TPGS and between 5 to 20 mg of the one or more purified cannabinoids and one or more terpenes per mL of water. (0)

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Patent US10722490

Water soluble compositions comprising purified cannabinoids

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