Abstract: |
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA sequencing to identify personalized biomarkers in patients with autoimmune disease and other conditions. Identified biomarkers can be used to determine the disease state for a subject with an autoimmune disease or other condition. |
Inventor: |
Faham, Malek (Pacifica, CA, US); Willis, Thomas (San Francisco, CA, US) |
Applicant: |
Adaptive Biotechnologies Corp. (Seattle, WA, US) |
Face Assignee: |
ADAPTIVE BIOTECHNOLOGIES CORP. (Seattle, WA, US) |
Filed: |
2016-01-04 |
Issued: |
2019-04-23 |
Claims: |
8 |
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US10266901
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1. A method for determining a profile of recombined T cell receptor (TCR) and/or immunoglobulin (IG) DNA sequences in a sample comprising T cells and/or B cells comprising:
(4)
(5)
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