Application US20210100999 AI Biotech/Diagnostics: General Diagnostics

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Cala Health, Inc. | Website | Headquarters: Burlingame, CA

Application US20210100999

Published 2021-04-08

Devices And Methods For Controlling Tremor

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. The peripheral nerve stimulator can be either a noninvasive surface stimulator or an implanted stimulator. Stimulation can be electrical, mechanical, or chemical. Stimulation can be delivered using either an open loop system or a closed loop system with feedback.

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4 Independent Claims

1-19. (canceled)
20. A method for transcutaneously stimulating afferent peripheral nerves of a stroke patient, the method comprising: measuring one or more characteristics of a tremor of the patient using one or more wearable sensors; analyzing data from the one or more wearable sensors to calculate a fraction of a period of the tremor; positioning a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve; positioning a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve; delivering a first electrical stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and delivering a second electrical stimulus to the second afferent peripheral nerve through the second peripheral nerve effector, wherein the second electrical stimulus is offset in time from the first electrical stimulus by the calculated fraction of the tremor period, wherein the calculated fraction is at least about a quarter of the tremor period.
28. A method for transcutaneously stimulating afferent peripheral nerves of a patient, the method comprising: measuring one or more characteristics of a resonant circuit of the patient using one or more wearable sensors; analyzing data from the one or more wearable sensors to calculate a fraction of a period of the resonant circuit; positioning a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve; positioning a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve; delivering a first electrical stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and delivering a second electrical stimulus to the second afferent peripheral nerve through the second peripheral nerve effector, wherein the second electrical stimulus is offset in time from the first electrical stimulus by the calculated fraction of the period of the resonant circuit, wherein the calculated fraction is selected from the group consisting of one half of the period of the resonant circuit, one quarter of the period of the resonant circuit, and three fourths of the period of the resonant circuit.
36. A system for transcutaneously stimulating afferent peripheral nerves, the system comprising: one or more wearable sensors measuring one or more characteristics of a resonant circuit of the patient; a controller configured to analyze data from the one or more wearable sensors to calculate a fraction of a period of the resonant circuit; a first peripheral nerve effector on the patient's skin to stimulate a first afferent peripheral nerve; a second peripheral nerve effector on the patient's skin to stimulate a second afferent peripheral nerve, wherein the controller is configured to cause the system to: deliver a first stimulus to the first afferent peripheral nerve through the first peripheral nerve effector; and deliver a second stimulus to the second afferent peripheral nerve through the second peripheral nerve effector, wherein the second stimulus is offset in time from the first electrical stimulus by the calculated fraction of the period of the resonant circuit, wherein the calculated fraction is selected from the group consisting of one half of the period of the resonant circuit, one quarter of the period of the resonant circuit, and three fourths of the period of the resonant circuit.