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AI Biotech/Diagnostics: Cardio

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Application US20180122515


Published 2018-05-03

Method And System For Microbiome-derived Characterization, Diagnostics And Therapeutics For Cutaneous Conditions

A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.



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2 Independent Claims

  • 1. A method for characterizing a dermatomyositis condition, the method comprising: receiving an aggregate set of samples from a population of subjects; for the aggregate set of samples: determining microorganism nucleic acid sequences, comprising: identifying a set of primers for nucleic acid sequences associated with the dermatomyositis condition, amplifying nucleic acid material from the aggregate set of sample samples based on the set of primers; and determining alignments of the microorganism nucleic acid sequences to reference sequences associated with the dermatomyositis condition; generating a microbiome feature dataset for the population of subjects based upon the alignments; generating a characterization model of the dermatomyositis condition from the microbiome feature dataset; based upon the characterization model, generating a therapy model that determines a therapy for correcting the dermatomyositis condition; and at an output device associated with the subject, providing the therapy to a subject diagnosed with the dermatomyositis condition based upon the characterization model and the therapy model.

  • 15. A method for diagnosing and treating a dermatomyositis condition of a subject, the method comprising: receiving a sample from the subject; determining nucleic acid sequences of a microorganism component of the sample upon amplifying nucleic acid material of the sample with a primer; generating a microbiome feature dataset for the subject based upon the nucleic acid sequences of the microorganism component; generating a characterization of the dermatomyositis condition in the subject upon processing the microbiome feature dataset with a characterization model derived from a population of subjects; and at an output device associated with the subject, providing a therapy to the subject with the dermatomyositis condition upon processing the characterization with a therapy model.