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AI Biotech/Diagnostics: General Diagnostics


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Application US20190159716


Published 2019-05-30

Cognitive Platform Including Computerized Evocative Elements

An apparatus for generating a quantifier of cognitive skills in an individual includes a user interface, a memory to store processor-executable instructions, and a processing unit communicatively coupled to the user interface and the memory. Upon execution of the processor-executable instructions by the processing unit, the processing unit is configured to: render a first instance of a task with an interference at the user interface, requiring a first response from the individual to the first instance of the task in the presence of the interference and a response from the individual to at least one evocative element. One or more of the first instance of the task and the interference comprises the at least one evocative element. The user interface is configured to measure data indicative of the response of the individual to the at least one evocative element, the data comprising at least one measure of emotional processing capabilities of the individual under emotional load. The apparatus is configured to measure substantially simultaneously the first response from the individual to the first instance of the task and the response from the individual to the at least one evocative element. The processing unit is further configured to receive data indicative of the first response and the response of the individual to the at least one evocative element. The processing unit is further configured to analyze the data indicative of the first response and the response of the individual to the at least one evocative element to compute at least one performance metric comprising at least one quantified indicator of cognitive abilities of the individual under emotional load.



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3 Independent Claims

  • 1. An apparatus for generating a quantifier of cognitive skills in an individual, said apparatus comprising: a user interface; a memory to store processor-executable instructions; and a processing unit communicatively coupled to the user interface and the memory, wherein upon execution of the processor-executable instructions by the processing unit, the processing unit is configured to: render a first instance of a task with an interference at the user interface, requiring a first response from the individual to the first instance of the task in the presence of the interference and a response from the individual to at least one evocative element; wherein: one or more of the first instance of the task and the interference comprises the at least one evocative element; the user interface is configured to measure data indicative of the response of the individual to the at least one evocative element, the data comprising at least one measure of emotional processing capabilities of the individual under emotional load; and the apparatus is configured to measure substantially simultaneously the first response from the individual to the first instance of the task and the response from the individual to the at least one evocative element; receive data indicative of the first response and the response of the individual to the at least one evocative element; and analyze the data indicative of the first response and the response of the individual to the at least one evocative element to compute at least one performance metric comprising at least one quantified indicator of cognitive abilities of the individual under emotional load.

  • 34. An apparatus for enhancing cognitive skills in an individual, said apparatus comprising: a user interface; a memory to store processor-executable instructions; and a processing unit communicatively coupled to the user interface and the memory, wherein upon execution of the processor-executable instructions by the processing unit, the processing unit is configured to: render a first instance of a task with an interference at the user interface at a first difficulty level, requiring a first response from the individual to the first instance of the task in the presence of the interference; wherein: one or more of the first instance of the task and the interference comprise at least one evocative element; the user interface is configured to measure data indicative of a response of the individual to the at least one evocative element, the data comprise at least one measure of a degree of emotional processing of the individual under emotional load; and the apparatus is configured to measure substantially simultaneously the first response from the individual to the first instance of the task and the response to the at least one evocative element; receive data indicative of the first response, and the response of the individual to the at least one evocative element; analyze the data indicative of the first response and the response of the individual to the at least one evocative element to compute a first performance metric representative of a performance of the individual under emotional load; adjust a difficulty of one or more of the task and the interference based on the computed at least one first performance metric such that the apparatus renders the task with the interference at a second difficulty level; and compute a second performance metric representative of cognitive abilities of the individual under emotional load based at least in part on the data indicative of the first response and the response of the individual to the at least one evocative element.

  • 76. An apparatus for enhancing cognitive skills in an individual, said apparatus comprising: a user interface; a memory to store processor-executable instructions; and a processing unit communicatively coupled to the user interface and the memory, wherein upon execution of the processor-executable instructions by the processing unit, the processing unit is configured to: receive data indicative of one or more of an amount, concentration, or dose titration of a pharmaceutical agent, drug, or biologic being or to be administered to an individual; render an instance of a task with an interference at the user interface, requiring a first response from the individual to the first instance of the task in the presence of the interference, wherein: one or more of the first instance of the task and the interference comprise at least one evocative element; the user interface is configured to measure data indicative of a response of the individual to the at least one evocative element, the data comprise at least one measure of a degree of emotional processing of the individual under emotional load; and the apparatus is configured to measure substantially simultaneously the first response from the individual to the first instance of the task and the response to the at least one evocative element; receive data indicative of the first response and the response of the individual to the at least one evocative element; analyze the data indicative of the first response and the response of the individual to the at least one evocative element to compute at least one performance metric comprising at least one quantified indicator of cognitive abilities of the individual under emotional load; and based at least in part on the at least one performance metric, generate an output to the user interface indicative of at least one of: (i) a likelihood of the individual experiencing an adverse event in response to administration of the pharmaceutical agent, drug, or biologic, (ii) a recommended change in one or more of the amount, concentration, or dose titration of the pharmaceutical agent, drug, or biologic, (iii) a change in the individual's cognitive response capabilities, (iv) a recommended treatment regimen, or (v) a recommended or determined degree of effectiveness of at least one of a behavioral therapy, counseling, or physical exercise.