Conversion Of Cbd To .delta..sup.8-thc And .delta..sup.9-thc
Methods of converting cannabidiol to .DELTA..sup.8-tetrahydrocannabinol or .DELTA..sup.9-tetrahydrocannabinol are described. The described methods produce higher yields and higher purity compared to prior art methods.
Claim 1. A method of converting cannabidiol (CBD) to .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC) comprising: providing a reaction mixture comprising CBD in drymethylene chlorideadding BF.sub.3Et.sub.2O to the reaction mixturestirring the ice cold reaction mixture under a nitrogen atmosphereadding NaHCO.sub.3 to the reaction mixtureallowing the mixture to separate into an aqueous phase and anorganic phaseremoving the organic phasewashing the organic layer with waterand eluting .DELTA..sup.9-THC from the organic phase, purity of the eluted .DELTA..sup.9-THC being greater than 97%.