The present disclosure relates to the production of cannabinoids in yeast. In as aspect there is provided a genetically modified yeast comprising: one or more GPP producing genes and optionally, one or more GPP pathway genes; two or more olivetolic acid producing genes; one or more cannabinoid precursor or cannabinoid producing genes; one or more Hexanoyl-CoA producing genes, and at least 5% dry weight of fatty acids or fats.
Claim CLM-00001. 1. A genetically modified yeast comprising:
(a) one or more GPP producing genes and optionally, one or more GPP pathway genes; (b) two or more olivetolic acid producing genes; (c) one or more cannabinoid precursor or cannabinoid producing genes; (d) one or more Hexanoyl-CoA producing genes, and (e) at least 5% dry weight of fatty acids or fats.