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Application US20200330378
Published 2020-10-22
Taste-enhanced Cannabinoid Submicron Emulsion Syrup Compositions
The present invention provides a stable oil-in-water submicron emulsion oral cannabinoid composition, comprising at least one cannabinoid in a pharmaceutically acceptable carrier, at least one triglyceride oil, at least two emulsifiers, at least one taste-enhancing excipient and water, wherein the composition is essentially free of bitter taste, and is essentially free of phospholipids, liposomes and/or micelles. The present invention also encompasses methods and a kit based on said composition.
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- 1. A stable oil-in-water submicron emulsion oral cannabinoid composition, comprising from about 0.05% w/w to about 10% w/w of at least one cannabinoid in a pharmaceutically acceptable carrier, from about 1% w/w to about 10% w/w of at least one triglyceride oil, from about 1% w/w to about 10% w/w of at least two emulsifiers, of which one having an HLB value from about 10 to about 16 and the other(s) having an HLB from about 2 to about 8, from about 1% w/w to about 40% w/w of at least one taste-enhancing excipient and from about 1% w/w to about 60% w/w of water,
wherein the composition is essentially free of bitter taste, and wherein the ratio between the at least one cannabinoid and the at least two emulsifiers is at least 1:5, and wherein the emulsion oil phase comprises not more than 10% by weight of the composition and wherein the composition is essentially free of phospholipids, liposomes and/or micelles.
