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AI Biotech/Diagnostics: Neurology

Search All Applications in AI Biotech/Diagnostics: Neurology


Application 20200306494


Published 2020-10-01

Enhancing Deep Sleep Based On Information From Frontal Brain Activity Monitoring Sensors

Typically, high NREM stage N3 sleep detection accuracy is achieved using a frontal electrode referenced to an electrode at a distant location on the head (e.g., the mastoid, or the earlobe). For comfort and design considerations it is more convenient to have active and reference electrodes closely positioned on the frontal region of the head. This configuration, however, significantly attenuates the signal, which degrades sleep stage detection (e.g., N3) performance. The present disclosure describes a deep neural network (DNN) based solution developed to detect sleep using frontal electrodes only. N3 detection is enhanced through post-processing of the soft DNN outputs. Detection of slow-waves and sleep micro-arousals is accomplished using frequency domain thresholds. Volume modulation uses a high-frequency/low-frequency spectral ratio extracted from the frontal signal.


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2 Independent Claims

  • Independent Claim 1. A system configured to enhance non-rapid eye movement (NREM) sleep by delivering sensory stimulation to a subject during a sleep session, the system comprising: first and second sensors configured to generate output signals conveying information related to brain activity of the subject during the sleep session, the first and second sensors configured to engage a forehead of the subjectone or more sensory stimulators configured to provide the sensory stimulation to the subject during the sleep sessionand one or more hardware processors coupled to the first and second sensors and the one or more sensory stimulators, the one or more hardware processors configured by machine-readable instructions to: detect NREM sleep in the subject during the sleep session based on the output signals from the first and second sensors, and control the one or more sensory stimulators to provide the sensory stimulation to the subject during the NREM sleep to enhance the NREM sleep in the subject during the sleep session.

  • Independent Claim 9. A method for enhancing non-rapid eye movement (NREM) sleep by delivering sensory stimulation to a subject during a sleep session with an enhancement system, the system comprising first and second sensors, one or more sensory stimulators, and one or more hardware processors coupled to the first and second sensors and the one or more sensory stimulators, the method comprising: generating, with the first and second sensors, output signals conveying information related to brain activity of the subject during the sleep session, the first and second sensors configured to engage a forehead of the subjectdetecting, with the one or more hardware processors, NREM sleep in the subject during the sleep session based on the output signals from the first and second sensorsand controlling, with the one or more processors, the one or more sensory stimulators to provide the sensory stimulation to the subject during the NREM sleep to enhance the NREM sleep in the subject during the sleep session.